Gold nanorod vaccine for respiratory syncytial virus
نویسندگان
چکیده
منابع مشابه
Need for a safe vaccine against respiratory syncytial virus infection
Human respiratory syncytial virus (HRSV) is a major cause of severe respiratory tract illnesses in infants and young children worldwide. Despite its importance as a respiratory pathogen, there is currently no licensed vaccine for HRSV. Following failure of the initial trial of formalin-inactivated virus particle vaccine, continuous efforts have been made for the development of safe and efficaci...
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Although RSV has been a high priority for vaccine development, efforts to develop a safe and effective vaccine have yet to lead to a licensed product. Clinical and epidemiologic features of RSV disease suggest there are at least 4 distinct target populations for vaccines, the RSV naïve young infant, the RSV naïve child ≥ 6 months of age, pregnant women (to provide passive protection to newborns...
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Bovine respiratory syncytial virus (BRSV) and human respiratory syncytial virus (HRSV) are major causes of respiratory disease in calves and children, respectively, and are priorities for vaccine development. We previously demonstrated that an experimental vaccine, BRSV-immunostimulating complex (ISCOM), is effective in calves with maternal antibodies. The present study focuses on the antigenic...
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Respiratory Syncytial Virus (RSV) is a major cause of severe lower respiratory tract infections in infants and children, leading to hospitalization of an estimated >3 million children under the age of 5 annually [1]. Despite such staggering figures, there is currently no licensed RSV vaccine. In the 1960s, a formalin-inactivated RSV vaccine candidate disastrously led to exacerbated disease [2]....
متن کاملHuman and bovine respiratory syncytial virus vaccine research and development.
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively. BRSV vaccines have been available for nearly 2 decades. They probably have reduced the prevalence of RSV infection but their efficacy needs improvement. In contrast, despite d...
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ژورنال
عنوان ژورنال: Nanotechnology
سال: 2013
ISSN: 0957-4484,1361-6528
DOI: 10.1088/0957-4484/24/29/295102